Anti Lamin A C Santa Cruz

Sc 6215 lamin a c antibody n 18 this product has been discontinued by santa cruz biotechnology but remains here on citeab for record purposes.

Anti lamin a c santa cruz.

Cited in 81 publications. Sc 7292 santa cruz biotechnology inc. 405326 at 2 0 µg ml. This antibody sc 7292 lamin a c 636 is produced by santa cruz biotechnology and is a non hazardous products for which no sds is required.

The expected protein mass is 74 1 kda but there are 6 reported isoforms. Santa cruz biotechnology inc. Santa cruz biotechnology goat anti lamin a c goat anti lamin a c supplied by santa cruz biotechnology used in various techniques. The cleavage of lamins results in nuclear dysregulation and cell death 5 6.

2000 j struct biol 129 313 23. P53 induces senescence through lamin a c stabilization mediated nuclear deformation. This clone e 1 is the strongest of the three santa cruz lamin a c antibodies that i have tested. Yoon m kang s lee s woo t oh a park s et al.

In humans this protein is encoded by the gene lmna. Our primary antibodies are provided in a solution of 1x pbs 0 1 sodium azide and 0 1 gelatin. 401402 panel a or purified anti lamin a c antibody clone wl4g10 panel b overnight at 4 c followed by incubation with alexa fluor 594 goat anti mouse igg cat. 89 100 based on 20 pubmed citations.

Cells were then intracellularly stained with a 1 100 dilution 5 µg ml of either purified mouse igg1 κ isotype control antibody cat. During apoptosis lamin a c is specifically cleaved into a large 41 50 kda and a small 28 kda fragment 3 4. Anti lamin a c antibodies are available from several suppliers. Lamin a c is cleaved by caspase 6 and serves as a marker for caspase 6 activation.